Tag Archives: Clinical trial

Vitamin B Supplements May Guard Against Stroke.

medicine_2Some studies suggest that vitamin B supplements may increase the risk of stroke and heart attack. However, a new review published in the journal Neurology discovered the opposite. Researchers analyzed the findings of 14 clinical trials which compared taking vitamin B supplement or very low-dose vitamin B versus placebo for six or more months. They discovered that vitamin B supplements may reduce the risk of stroke by 7 percent, but did not appear to reduce the severity of strokes or the risk of death from stroke. The researchers also found that folic acid may reduce the beneficial effect of vitamin B. How often do patients ask you about vitamin B supplements? Do you recommend vitamin B for other conditions?

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Calcium and vitamin D fail to relieve joint pain in study.

bone_kneeAlthough some studies suggest that low levels of vitamin D are associated with joint pain and swelling,a post-hoc analysis of the Women’s Health Initiative clinical trial suggest that vitamin D-3 (400IU) and calciumcarbonate (1000mg elemental calcium) are no better than placebo for relieving joint problems. After two years, 74.6% of the supplement group still had joint pain, compared to 75.1% of the placebo group.  What has vitamin D and calcium been most effective for in your patients?

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Sodium, Blood Pressure and Cardiovascular Disease

The American Heart Association (AHA) Presidential Advisory just released its report on sodium use in patients with cardiovascular disease.  The report was based on experimental and laboratory studies, US population surveys, observational and clinical trials and nutritional adequacy analysis. The evaluation of data was instigated by a recent controversial evidence suggesting removal of previous AHA sodium reduction recommendations.  Based on all the currently available evidence, AHA Presidential Advisory recommends reducing dietary sodium intake to <1500 mg/day in US population. How do you encourage your patients to reduce their dietary sodium intake?

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