A single injection of the natural hormone, kisspeptin might replace the need for human chorionic gonadotropin (hCG) hormone in in-vitro fertilization. Ten of 53 women in a recent study gave birth, with 2 women giving birth to twins. The hCG triggers egg maturation but can overstimulate the ovaries, but kisspeptin is broken down more quickly resulting in less overstimulation. Five adverse effects reported were 2 ectopic pregnancy, 2 miscarriages, and 1 heterotopic pregnancy. How do you feel about the use of kisspeptin as an alternative to hCG therapy?
For additional information, please see Journal of Clinical Investigation.